







Buy anything from 5,000+ international stores. One checkout price. No surprise fees. Join 2M+ shoppers on Desertcart.
Desertcart purchases this item on your behalf and handles shipping, customs, and support to Macau.
🐾 Clear ears, happy pets — because they deserve the best care!
Zymox Advanced Formula Otic Plus is a 1.25oz enzymatic ear solution for dogs and cats that combines the LP3 Enzyme System with 1% Hydrocortisone to effectively combat biofilms, relieve itching, and reduce redness. Its gentle, no-pre-cleaning formula offers a vet-recommended, odorless, and mess-free application trusted by thousands of pet owners to soothe persistent ear problems across all pet ages.






































| Customer Reviews | 4.7 out of 5 stars 14,748 Reviews |
Y**I
Fast Relief, Clean Application, No Strong Smell
My dog had been scratching one ear a lot, and it was getting hard to ignore. I wanted to try something at home first before going to the vet, so I gave this a shot. The bottle is simple and easy to handle, and the applicator tip helps keep things clean when applying it. The liquid itself is clear, slightly thick (not watery), and doesn’t really have a noticeable odor, which I liked because it didn’t bother my dog at all. After using it as directed, I noticed a difference pretty quickly. By the second use, he had already stopped scratching so much and seemed a lot more comfortable. That was honestly the biggest thing for me. What stood out is how clean the application feels (no mess), the texture of the product, and that it doesn’t have a strong scent. It also seems gentle enough, since my dog didn’t react negatively and stayed calm during use. One small thing is that you still have to apply it carefully, especially if your dog moves a lot. Seeing him relaxed again and not constantly scratching made a big difference. I’d definitely keep this on hand in case it happens again.
C**N
Best pet ear cleaning product on the market
I have been an Amazon customer for years and this may be the best product I have ever bought on Amazon. I have a cat that has had major ear problems for years. He's been to the vet on numerous locations who have treated him for infections as well as a deep cleaning of his ears and nothing has worked. I hate seeing my cat suffer like this so I decided to take a chance in this product. Well this miracle product works. I followed the directions exactly and used it for seven full days. I noticed an improvement after 3 days but after 7 days, the cat's ear problems are almost completely gone. Although he shakes his head from time to time, the itching is pretty much gone and his ears are much cleaner. I am now following this care with the Zymox ear cleaning pads from time to time. I highly recommend both of these products. Just follow the directions. Thank you Zymox!
J**R
Amazing product
I just wanna say this worked amazing on my pit bulls ears. My poor baby has had on going ear infections going from one ear to another. We have tried so many creams, drop, all that you can think of and some would help for a short while then the irritation would come back again. Within 3 days of use the redness, irritation and infection is gone. No more endless nights of ear shaking and scratching! Was very skeptical at first because of the price, but I will say it’s worth it money 100%
S**2
One happy dog mom. This stuff is amazing!! 🙌🏻
This stuff works!!!! My beagle has ear issues with itching bad and the head shakes. I had her taken in to the vet and it was cleaned out with meds added and I left with $100 or more vet bill. My poor beagle had issues again months later so I looked on Amazon and found an ear flush that is amazing, but the issue wasn’t fully going away. I then found this product and gave it a try. No more vet visits this stuff cleared up her ear problems. It went from inflammation and dirty looking to a clear ear that is so clean and no issues. My sweet girl is so happy now. I highly recommend this product if your dog has itching, inflammation and the head shaking due to their ear bother them. I can’t believe how quickly and well this cleared my dog’s ear. It’s a heavier gel product too so it stays put. There’s also so much product to use. This will be a good thing to keep on hand instead of a vet visit for ear issues.
K**E
Works well
My dog was visibly more comfortable after 36 hours, once I applied the ear drops. It didn’t smell, and was easy enough to apply.
E**E
A must-have for allergy dogs! Works fast without trapping moisture.
If you have a dog with severe atopic dermatitis, buy this!! My cutie schnauzer is currently on a strict allergy regimen (immunotherapy and Zenrelia). Her skin is managed well, but she recently started pawing at her head/ear. Her ear smelled awful :( I made the mistake of using a standard ear flush first, which just ended up trapped deep in her ear canal (I could hear the liquid squishing for days when massaging her ears). I decided to try this before making an $$ vet appointment. Within 2 days, the odor vanished completely and she is totally comfortable. This saved us so much stress and a costly trip to the clinic!
A**R
Best solution for dogs' itchy ear
My dog flapped his ears and used his paws to scratch his ears for about week time. I realized that there was something discomforting in his ears and I search this product. I applied it to my dog the first night and I can see the efficacy in the first night and continue the second night to apply the product to my dog's ear, then I did not see my dog scratch the ears any more. I think the product works perfect for the itchy ears. It is easy to apply without much discomfort, and no scent at all.
S**.
Really does work. Saves you money
We tried this product for his ear infection. By day 2 signs of significant improvement. By Day 4 his ear was healed. We continued use for the whole recommended time duration. Using this product saved us tons of money from a vet visit and bill.skin in ear looks great. No more irritation or shaking his head. We are very happy we purchased this for our Jake. First picture is of infection prior to usage , others are after usage.
J**S
Great product. Solved my dog’s ear problem quickly.
Wow! My dog had what I interpreted as excessive wax build up in his ear. He’s a feisty little guy and I could not get on top of it with mere cleaning and hair trimming. With a yeasty smell I turned to this product. The debris that came out of his ear was phenomenal, and now he is irritation free with a very clean ear canal. This product is highly recommended.
A**R
Cures ear infections at a low price
I haven’t had to go to the vet and pay hundreds of dollars for things to fix her ear infections since we got this stuff. I have a Chinese shar pei so it’s really common for them to get ear infections. This stuff is thick and doesn’t go everywhere, travels thru their ear and then you just wipe the excess. It’s great!
J**I
Excellent
Excellent product as describe
G**S
great product , great service
great product , seems to be working fine
B**Y
Cat yeasty ears
Had tried numerous different ways & products to rectify my cat’s yeasty ears which was giving her great irritation. Came across Zymox as a suggestion, applied once a day for 7 days- Problem solved immediately after one weeks use.! Even now a few weeks later she is irritation free and her ears are clear of black debris. Highly recommended.
Trustpilot
2 weeks ago
1 month ago