900MG Liposomal Sulforaphane Supplement Broccoli Extract, Liver Supplement for Antioxidant, Digestion, Cellular Health 60 Capsules

If you're not a big fan of broccoli, this is the nutrient you need for your colon and digestive health. So far, the supplement is been working for me and it doesn't even bloat me or cause any discomfort. No side effects after 2 months and size is perfect for my narrow throat.

Normally, when I use a product that comes in gummy form, I check the molecular weight of the active ingredient to see if it can pass the blood/brain barrier. Some products are not meant to have that function, even if they have the ability to do so. If the active ingredient is meant to pass the BBB I will normally use those gummies for buccal or sublingual absorption. Sulforaphane is meant to pass the BBB, so it can be used for buccal or sublingual absorption. That said, this particular product has a novel liposomal delivery system. To quote the product label: "Gummie-jel's dual layer design, with a protective pectin outer layer, stabilizes the fat soluble nutrients, while enhancing absorption for effective and overall vitality." Here is all you need to know about that: "Liposomes mimic natural cell membranes and have long been investigated as drug carriers due to excellent entrapment capacity, biocompatibility and safety. Despite the success of parenteral liposomes, oral delivery of liposomes is impeded by various barriers such as instability in the gastrointestinal tract, difficulties in crossing biomembranes, and mass production problems. By modulating the compositions of the lipid bilayers and adding polymers or ligands, both the stability and permeability of liposomes can be greatly improved for oral drug delivery." It seems to me that this brand of gummie has mastered that problem very well. Its ingenious delivery system can thus be swallowed whole with the confidence that the sulphoraphane will reach the small intestine, intact, where it can then pass into the blood stream directly. The problem there is that sulforaphane is filtered through the kidneys, as it is metabolized through the mercapturic acid pathway, which involves the kidney, liver, and small intestine. That begs the question, how much of the sulforaphane actually makes it to and past the BBB? Back when I had a large laboratory where I could address that question, I would do so, but for me, the easiest thing to do is to do as I have described and absorb the ingredients sublingually and/or buccally, knowing that they have a better chance of reaching the BBB intact. I did quite a bit of research on Sulforaphane supplements about a decade after they became well known. I began taking them around 10 years ago, but even then, sulforaphane wasn't well researched. The sulforaphane I was taking was expensive and I just gave up on it for that reason. When I was offered the Nextdia brand for evaluation through the Amazon Vine program, I decided to review the literature on sulforaphane and I was surprised at the volume of recent scientific research that has been done on it since I last looked into it. I invite you to do your own research (using, of course, Google Scholar) and then go to the pages where Sulforaphane is sold on AMAZON. Amazon has a huge array of choices since I first began using the product, and the most expensive one is still the most expensive and I don't find it to be any better than this Nextdia brand. I will evaluate and research further and I will update my review here if necessary.

I like that they have combined both Sulforaphane (SFN), along with glucoraphanin, its stable precursor. The enzyme myrosinase is also included, which converts glucoraphanin to SFN, for a bigger bang for the buck!

It’s recommended by many doctors. I take it continuously. The liposomal design improves its bioavailability. It doesn’t impact my digestion negatively.

I'm still not sure but this was one of the supplements that was suggested so do some research but this seems good quality and it's also seems like it's as advertised

I am early on taking this supplement. I have a leaky gut and the reason for ordering this supplement. The milligrams pointed me to this particular brand. I feel my gut is improving and I am hoping this is speeding it along. I feel it is a good supplement and will reorder it.

I use this Vitacrlly 900 mg liposomal sulforaphane supplement because it reduces my pelvic pain due to excess estrogen after menopause. I love that it's all natural and broccoli based. The price point of $9.99 is perfect! And that it has subscribe and Save! 😁 I just wish that the seller would do a little better about keeping it in stock.😏

I use them daily and like them much